Anti-COASY Polyclonal Antibody
产品名称： Anti-COASY Polyclonal Antibody
英文名称： Anti-COASY Polyclonal Antibody
产品编号： K002459P
产品价格： null
产品产地： 北京
品牌商标： solarbio
更新时间： 2025-03-04T13:05:03
使用范围： WB IHC
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
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- 邮箱 : 3193328036@qq.com
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Anti-COASY Polyclonal Antibody
品牌：solarbio | 货号：K002459P
| 英文名称 | Anti-COASY Polyclonal Antibody |
|---|---|
| 别名 | DPCK;NBIA6;NBP;PPAT;UKR1;pOV-2 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| 交叉反应 | Human Mouse Rat |
| 蛋白分子量 | 62kDa |
| Gene ID | 80347 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human COASY |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human COASY |
| Subcellular Locations | Cytoplasm Mitochondrion matrix |
| Swiss Prot | Q13057 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms. |