Anti-CD59 Polyclonal Antibody
产品名称： Anti-CD59 Polyclonal Antibody
英文名称： Anti-CD59 Polyclonal Antibody
产品编号： K002538P
产品价格： null
产品产地： 北京
品牌商标： solarbio
更新时间： 2025-03-04T13:05:03
使用范围： WB
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
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- 邮箱 : 3193328036@qq.com
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Anti-CD59 Polyclonal Antibody
品牌：solarbio | 货号：K002538P
| 英文名称 | Anti-CD59 Polyclonal Antibody |
|---|---|
| 别名 | 16.3A5;1F5;EJ16;EJ30;EL32;G344;HRF-20;HRF20;MAC-IP;MACIF;MEM43;MIC11;MIN1;MIN2;MIN3;MIRL;MSK21;p18-20 |
| 应用 | WB |
| 稀释比例 | WB 1:500-2000. |
| 交叉反应 | Human |
| 蛋白分子量 | 14kDa |
| Gene ID | 966 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human CD59 |
| 性状 | 液体 |
| Public Immunogen Range | Recombinant protein of human CD59 |
| Subcellular Locations | Cell membrane GPI-anchor Lipid-anchor Secreted |
| Swiss Prot | P13987 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. |